Ethyl methanesulfonate (EMS) is a potent, mutagenic, and carcinogenic alkylating agent widely used in genetics research to induce random point mutations, primarily to transitions. It functions by introducing an ethyl group to DNA bases, causing mispairing during replication.
Ethyl methanesulfonate is mutagenic to plants and animals and carcinogenic in mammals
Key Applications
Mutagenesis Studies
EMS is commonly used to induce random mutations in microorganisms, plants, and cell cultures by alkylating guanine bases in DNA.
Genetic Research
It helps generate mutant libraries for gene function studies and forward genetics research.
Plant Breeding Programs
EMS-induced mutations are used to create new plant varieties with improved traits.
Microbial Strain Improvement
Used in industrial microbiology to enhance enzyme production or metabolite yield.
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